IQ-3
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IQ-3

SKU T8477-1 mg Category Brand:

Price range: 54 CAD through 878 CAD

Products Details

Product Description

– IQ3 is a selective inhibitor of JNK3(JNK3, JNK1 and JNK2 with Kd of 66 nM, 240 nM and 290 nM, respectively). IQ 3 inhibits NF-κB/AP1 transcriptional activity in THP1-Blue cells with IC50 of 1.4 μM, also inhibits TNF-α and IL-6 production in vitro.

Web ID

– T8477

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H11N3O3

References

– Schepetkin I A , Kirpotina L N , Khlebnikov A I , et al. Identification and Characterization of a Novel Class of c-Jun N-terminal Kinase Inhibitors[J]. Molecular Pharmacology, 2012, 81(6):832-845.

CAS Number

– 312538-03-7

Molecular Weight

– C20H11N3O3

Compound Purity

– ≥98%

SMILES

– O=C(ON=C1c2ccccc2-c2nc3ccccc3nc12)c1ccco1

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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