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IPN60090
Price range: 171 CAD through 2,112 CAD
Products Details
Product Description
– IPN60090 is a novel, potent, orally bioavailable, renal-type glutaminase (GLS1)-specific inhibitor with an IC50 value of 31 nM for GLS1. IPN60090 has potential anticancer and immunostimulant/immunomodulatory activity, selectively targets, binds, and inhibits human glutaminase, and can be used to study GLS1-mediated diseases.
Web ID
– T11412
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H27F3N8O3
Citations
– 1. Gong K, Huang Y, Zheng Y, et al.ZSWIM4 inhibition improves chemosensitivity in epithelial ovarian cancer cells by suppressing intracellular glycine biosynthesis.Journal of Translational Medicine.2024, 22(1): 1-21.
References
– Maria Emilia Di Francesco, et al. Gls1 inhibitors for treating disease. WO2016004404A2.
CAS Number
– 1853164-83-6
Molecular Weight
– C24H27F3N8O3
Compound Purity
– 1
SMILES
– CNC(=O)c1cn(C[C@H](F)CCc2ccc(NC(=O)Cc3cc(OC4CC(F)(F)C4)cc(C)n3)nn2)nn1
Target
– ADC Linker
Pathway
– Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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