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Intepirdine
Price range: 54 CAD through 621 CAD
Products Details
Product Description
– Intepirdine (GSK-742457) is a highly selective 5-HT6 receptor antagonist, used in trials studying the treatment of Alzheimer’s Disease.
Web ID
– T1774
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H19N3O2S
Citations
– 1. Rychtyk J, Partyka A, Gdula-Argasińska J, et al. 5-HT6 receptor agonist and antagonist improve memory impairments and hippocampal BDNF signaling alterations induced by MK-801. Brain Research. 2019: 146375
2. Wesołowska A, Rychtyk J, Gdula-Argasińska J, et al Effect of 5-HT6 Receptor Ligands Combined with Haloperidol or Risperidone on Antidepressant-/Anxiolytic-Like Behavior and BDNF Regulation in Hippocampus and Prefrontal Cortex of Rats. Neuropsychiatric Disease and Treatment. 2021, 17: 2105.
4. Partyka A, Górecka K, Gdula-Argasińska J, et al.Selective 5-HT6 Receptor Ligands (Agonist and Antagonist) Show Different Effects on Antipsychotic Drug-Induced Metabolic Dysfunctions in Rats.Pharmaceuticals.2023, 16(2): 154.
References
– Chuang ATT, et al. Alzheimers Dement, 2006, 2, S631–S632 (abstract).
CAS Number
– 607742-69-8
Molecular Weight
– C19H19N3O2S
Compound Purity
– 0.9863
SMILES
– S(=O)(=O)(C1=CC2=C(C(=CC=C2)N3CCNCC3)N=C1)C4=CC=CC=C4
Target
– Epigenetic Reader Domain
Pathway
– Neuroscience|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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