Download Files:
Products Details
Product Description
– Integrase-LEDGF/p75 allosteric inhibitor 1 (Compound 31h) is an orally active integrase-LEDGF/p75 (IN-LEDGF/p75) allosteric inhibitor. Integrase-LEDGF/p75 allosteric inhibitor 1 inhibits HIV-1 DNA integration and shows antiviral activity with an EC50 of 3.9 nM against HIV-1 recombinant molecular clone NL432[1].
Web ID
– HY-147653
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C33H41NO6S
References
– [1]Sugiyama S, et al. Discovery of novel integrase-LEDGF/p75 allosteric inhibitors based on a benzene scaffold. Bioorg Med Chem. 2020 Sep 1;28(17):115643.
CAS Number
– 1431738-14-5
Molecular Weight
– 579.75
SMILES
– CC1=CC=C(C=C1C)C2=C(C(C3=CC=C4OCCCC4=C3C)=C(C(C)=C2NS(C)(=O)=O)C(C(O)=O)OC(C)(C)C)C
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV Integrase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
