INT-777 R-enantiomer
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INT-777 R-enantiomer

SKU T11662-25 mg Category Brand:

Price range: 2,912 CAD through 4,960 CAD

Products Details

Product Description

– INT-777 is the R-enantiomer of INT-777, less potent than INT-777,EC50 of 4.79 μM for TGR5.

Web ID

– T11662

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H46O5

References

– Pellicciari R, et al. Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity. J Med Chem. 2009 Dec 24;52(24):7958-6

CAS Number

– 1198786-98-9

Molecular Weight

– C27H46O5

SMILES

– [H][C@@]12CC[C@H]([C@H](C)C[C@@H](C)C(O)=O)[C@@]1(C)[C@@H](O)C[C@@]1([H])[C@@]2([H])[C@H](O)[C@H](CC)[C@]2([H])C[C@H](O)CC[C@]12C

Target

– ALK|||TGF-beta/Smad

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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