Indomethacin
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Indomethacin

SKU T0458-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 59 CAD through 261 CAD

Products Details

Product Description

– Indomethacin (Indomethacin) is a COX1 and COX2 inhibitor (IC50=18/26 nM) with blood-brain barrier permeability and non-selectivity. Indomethacin is a non-steroidal anti-inflammatory agent with anti-tumor and anti-infective activity.

Web ID

– T0458

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H16ClNO4

Citations

– 1. Bi X, Yan X, Jiang B, et al. Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses. Toxicology and Applied Pharmacology. 2021: 115778. 2. Chen F, Xu Y, Wang J, et al. Relaxation Effect of Patchouli Alcohol in Rat Corpus Cavernous and Its Underlying Mechanisms. Evidence-Based Complementary and Alternative Medicine. 2020. 3. Yan Z, Ruan B, Wang S, et al.RNA-binding Protein QKI Inhibits Osteogenic Differentiation Via Suppressing Wnt Pathway.Archives of Medical Research.2023: 102853.

References

– Dihlmann S, et al. Oncogene, 2001, 20(5), 645-653.

CAS Number

– 53-86-1

Molecular Weight

– C19H16ClNO4

Compound Purity

– 0.9984

SMILES

– COC1=CC2=C(C=C1)N(C(=O)C1=CC=C(Cl)C=C1)C(C)=C2CC(O)=O

Target

– Others

Pathway

– Metabolism|||Neuroscience|||Immunology/Inflammation|||Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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