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Products Details
Product Description
– iMDK quarterhydrate is a potent PI3K inhibitor that inhibits the growth factor MDK (also known as midkine or MK). iMDK quarterhydrate synergistically inhibits non-small cell lung cancer (NSCLC) with MEK inhibitors without harming normal cells and mice.
Web ID
– T9460
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H13FN2O2S
Citations
– 1. Wan Z, Bai X, Wang X, et al.Mgp High‐Expressing MSCs Orchestrate the Osteoimmune Microenvironment of Collagen/Nanohydroxyapatite‐Mediated Bone Regeneration.Advanced Science.2024: 2308986.
References
– Naomasa Ishida, et al. A novel PI3K inhibitor iMDK suppresses non-small cell lung Cancer cooperatively with A MEK inhibitor. Exp Cell Res. 2015 Jul 15;335(2):197-206.
CAS Number
– 881970-80-5
Molecular Weight
– C21H13FN2O2S
Compound Purity
– 0.9999
SMILES
– Fc1ccc(Cc2cn3cc(nc3s2)-c2cc3ccccc3oc2=O)cc1
Pathway
– PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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