Imatinib-d8

SKU T11640-1 mg Category Brand:

Price range: 653 CAD through 2,990 CAD

Products Details

Product Description

– Imatinib-d8 (STI571 D8) is a 2H-labeled version of Imatinib. Imatinib is a multi-target receptor tyrosine kinase inhibitor with anti-tumor activity, selectively inhibiting BCR-ABL, v-Abl, PDGFR, c-kit kinases, and is used in chronic myeloid leukemia treatment.

Web ID

– T11640

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H23D8N7O

References

– Heinrich MC, et al. Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor. Blood. 2000 Aug 1;96(3):925-32.

CAS Number

– 1092942-82-9

Molecular Weight

– C29H23D8N7O

SMILES

– N(C=1N=C(C=CN1)C=2C=CC=NC2)C3=CC(NC(=O)C4=CC=C(CN5C(C(N(C)C(C5([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C=C4)=CC=C3C

Target

– GSK-3

Pathway

– Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Autophagy|||Microbiology/Virology

Product type

– Isotope products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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