Products Details

Product Description

– IHR-Cy3 is a potent fluorescent Smo antagonist with an IC50 of 100 nM[1].

Web ID

– HY-131016

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C58H63Cl3N6O10S2

References

– [1]Chih-Wei Fan, et al. The Hedgehog Pathway Effector Smoothened Exhibits Signaling Competency in the Absence of Ciliary Accumulation. Chem Biol

Molecular Weight

– 1174.64

SMILES

– ClC1=CC=C(C(C(NC2=CC=C(C=C2)NC(C3=C(C=CC(NC(CCCCCCNC(CCCCC[N+]4=C(C(C)(C5=C4C=CC(S(=O)(O)=O)=C5)C)/C=C/C=C6N(C7=C(C/6(C)C)C=C(S(=O)([O-])=O)C=C7)CC)=O)=O)=C3)Cl)=O)=O)=C1)Cl

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Smo

Pathway

– Stem Cell/Wnt

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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