iFSP1
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iFSP1

SKU T11631-5 mg Category Brand:

Price range: 46 CAD through 525 CAD

Products Details

Product Description

– iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse human cancer cell lines to ferroptosis inducers like (1S,3R)-RSL3. It uniquely triggers ferroptosis in GPX4-knockout cells overexpressing FSP1.

Web ID

– T11631

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H13N5

Citations

– 1. Shi Y, Xu N, Liu B, et al.Mifepristone protects acetaminophen induced liver injury through NRF2/GSH/GST mediated ferroptosis suppression.Free Radical Biology and Medicine.2024

References

– Doll S, et al. FSP1 is a glutathione-independent ferroptosis suppressor.Nature. 2019 Nov;575(7784):693-698.

CAS Number

– 150651-39-1

Molecular Weight

– C20H13N5

Compound Purity

– 0.9874

SMILES

– Cc1ccc(cc1)-c1c(C#N)c(N)n2c3ccccc3nc2c1C#N

Target

– ADC Linker

Pathway

– Apoptosis

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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