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IEM-1460

$80$450

Products Details

Product Description

– IEM-1460 blocks both AMPA and NMDA glutamate receptor with anticonvulsant effect in vivo[1].

Web ID

– HY-103230

Shipping

– Room temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C19H38Br2N2

References

– [1]Schlesinger F, et al. Two mechanisms of action of the adamantane derivative IEM-1460 at human AMPA-type glutamate receptors. Br J Pharmacol. 2005 Jul;145(5):656-63.

CAS Number

– 121034-89-7

Molecular Weight

– 454.33

SMILES

– C[N+](C)(C)CCCCCNCC12C[C@H](C3)C[C@H](C[C@H]3C2)C1.Br.[Br-]

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– iGluR

Isoform

– AMPA Receptor

Pathway

– Membrane Transporter/Ion Channel;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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