Products Details

Product Description

– IDD388 is a selective aldose reductase (ALR2) inhibitor with an IC50 of 30 nM. IDD388 displays selectivity for ALR2 over ALR1 (IC50 of 14 μM)[1].

Web ID

– HY-121933

Shipping

– Room temperature

Molecular Formula

– C16H12BrClFNO4

References

– [1]Holger Steuber, et al. Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features. J Mol Biol. 2008 Jun 20;379(5):991-1016.

CAS Number

– 314297-26-2

Molecular Weight

– 416.63

SMILES

– O=C(COC1=CC(Cl)=CC=C1C(NCC2=CC=C(C=C2F)Br)=O)O

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– 10 mM in DMSO

Target

– Aldose Reductase

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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