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IDD388
SKU
HY-121933-Get quote
Category Reference compound
Tags Aldose Reductase, Metabolic Disease, Metabolic Enzyme/Protease
Products Details
Product Description
– IDD388 is a selective aldose reductase (ALR2) inhibitor with an IC50 of 30 nM. IDD388 displays selectivity for ALR2 over ALR1 (IC50 of 14 μM)[1].
Web ID
– HY-121933
Shipping
– Room temperature
Molecular Formula
– C16H12BrClFNO4
References
– [1]Holger Steuber, et al. Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features. J Mol Biol. 2008 Jun 20;379(5):991-1016.
CAS Number
– 314297-26-2
Molecular Weight
– 416.63
SMILES
– O=C(COC1=CC(Cl)=CC=C1C(NCC2=CC=C(C=C2F)Br)=O)O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Aldose Reductase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
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