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iCRT-5
$450 – $720
Products Details
Product Description
– iCRT-5 is a β-catenin-regulated transcription (CRT) inhibitor. iCRT-5 can block Wnt/β-catenin reporter activity and down regulate β-catenin expression. iCRT-5 can be used for the research of multiple myeloma[1][2].
Web ID
– HY-119383
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H17NO5S2
References
– [1]Käfer R, et, al. Inhibitors of β-catenin affect the immuno-phenotype and functions of dendritic cells in an inhibitor-specific manner. Int Immunopharmacol. 2016 Mar;32:118-124.|[2]Narayanan BA, et, al. Antagonistic effect of small-molecule inhibitors of Wnt/β-catenin in multiple myeloma. Anticancer Res. 2012 Nov;32(11):4697-707.
CAS Number
– 18623-44-4
Molecular Weight
– 367.44
Compound Purity
– 99.0
SMILES
– O=C(O)CCCN(C/1=O)C(SC1=C/C2=CC=C(OC)C(OC)=C2)=S
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 36 mg/mL (ultrasonic;warming)
Target
– β-catenin
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
