ICG-001
Add to CompareAdded to Compare

Download Files:

ICG-001

SKU T6113-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 2,016 CAD

Products Details

Product Description

– ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction without interfering with β-catenin/p300 interaction. It specifically binds to CREB protein with an IC50 of 3 μM.

Web ID

– T6113

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C33H32N4O4

Citations

– 1. Miao H, Wang Y, Su W, et al.Sirtuin 6 protects against podocyte injury by blocking the renin-angiotensin system by inhibiting the Wnt1/β-catenin pathway.Acta Pharmacologica Sinica.2023: 1-13. 2. Yu Z, Gao R, Lv C, et al.Notoginsenoside R1 promotes Lgr5+ stem cell and epithelium renovation in colitis mice via activating Wnt/β-Catenin signaling.Acta Pharmacologica Sinica.2024: 1-15.

References

– Emami KH, et al, Proc Natl Acad Sci USA, 2004, 101(34), 12682-12687.

CAS Number

– 780757-88-2

Molecular Weight

– C33H32N4O4

Compound Purity

– 0.9959

SMILES

– Oc1ccc(C[C@@H]2N3[C@H](CN(Cc4cccc5ccccc45)C2=O)N(CCC3=O)C(=O)NCc2ccccc2)cc1

Pathway

– Apoptosis|||Cytoskeletal Signaling|||Chromatin/Epigenetic|||Stem Cells

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
Mecarbinate
Mecarbinate Price range: 46 CAD through 56 CAD
1 g1 mL * 10 mM (in DMSO)

1000 in stock

Select options
Procainamide hydrochloride
Procainamide hydrochloride Price range: 50 CAD through 317 CAD
1 g1 mL * 10 mM (in DMSO)25 mg

1000 in stock

Select options
Ethamsylate
Ethamsylate 46 CAD
1 mL * 10 mM (in DMSO)50 mg

1000 in stock

Select options
7-Chloro-4-(piperazin-1-yl)quinoline
7-Chloro-4-(piperazin-1-yl)quinoline Price range: 56 CAD through 77 CAD
100 mg200 mg

1000 in stock

Select options
3-Acetylcoumarin
3-Acetylcoumarin 46 CAD
1 mL * 10 mM (in DMSO)500 mg

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });