Products Details

Product Description

– icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 does not competitively inhibit FSP1 enzyme activity, but instead triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1].

Web ID

– HY-157068

Shipping

– Room temperature

Molecular Formula

– C26H25N3O5

References

– [1]Toshitaka Nakamura, et al. Phase separation of FSP1 promotes ferroptosis. Nature. 2023 Jul;619(7969):371-377.

CAS Number

– 1115910-36-5

Molecular Weight

– 459.49

SMILES

– O=C1C2=C(N=C(C)N1C3=CC=C(NC(CC4=CC(OC)=C(C(OC)=C4)OC)=O)C=C3)C=CC=C2

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Ferroptosis

Pathway

– Apoptosis

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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