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ICA
$180 – $2,640
Products Details
Product Description
– ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 µM.
Web ID
– HY-22044
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C13H10N4S
References
– [1]Bhuniya D, et al. Aminothiazoles: Hit to lead development to identify antileishmanial agents. Eur J Med Chem. 2015 Sep 18;102:582-93.|[2]Skibsbye L, et al. Antiarrhythmic Mechanisms of SK Channel Inhibition in the Rat Atrium. J Cardiovasc Pharmacol. 2015 Aug;66(2):165-76.
CAS Number
– 3374-88-7
Molecular Weight
– 254.31
Compound Purity
– 99.63
SMILES
– C1(NC2=NC(C3=NC=CC=C3)=CS2)=NC=CC=C1
Clinical Information
– No Development Reported
Research Area
– Infection; Cardiovascular Disease
Solubility
– DMSO : ≥ 49.5 mg/mL
Target
– Parasite
Isoform
– Leishmania
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
