IBMX
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IBMX

SKU T1713-1 mL * 10 mM (in DMSO) Category Tag Brand:

Price range: 53 CAD through 168 CAD

Products Details

Product Description

– IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 μM). IBMX enhances the intracellular cAMP level.

Web ID

– T1713

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C10H14N4O2

Citations

– 1. Yan Z, Ruan B, Wang S, et al.RNA-binding Protein QKI Inhibits Osteogenic Differentiation Via Suppressing Wnt Pathway.Archives of Medical Research.2023: 102853.2. Chen S, Zhou X, Li W, et al.Development of a novel peptide targeting GPR81 to suppress adipocyte-mediated tumor progression.Biochemical Pharmacology.2023: 115800.3. Lin S, Zhong L, Chen J, et al.GDF11 inhibits adipogenesis of human adipose-derived stromal cells through ALK5/KLF15/β-catenin/PPARγ cascade.Heliyon.2023: e13088.4. Sun C, Li X, Guo E, et al. MCP-1/CCR-2 axis in adipocytes and cancer cell respectively facilitates ovarian cancer peritoneal metastasis. Oncogene. 2019: 1-15.5. Xiaoli F, Yaqing Z, Ruhui L, et al. Graphene oxide disrupted mitochondrial homeostasis through inducing intracellular redox deviation and autophagy-lysosomal network dysfunction in SH-SY5Y cells. Journal of Hazardous Materials. 2021: 126158.6. Zhang Y, Pu Y, Deng Y, et al.Therapeutic of a white adipose tissue-specific bivalent aptamer in obesity.Biochemical Pharmacology.2024: 116452.

References

– Wei Y, et al. Angiotensin II type 2 receptor regulates ROMK-like K⁺ channel activity in the renal cortical collecting duct during high dietary K⁺ adaptation. Am J Physiol Renal Physiol. 2014 Oct 1;307(7):F833-43.

CAS Number

– 28822-58-4

Molecular Weight

– C10H14N4O2

Compound Purity

– 0.9997

SMILES

– CC(C)Cn1c2[nH]cnc2c(=O)n(C)c1=O

Target

– Endogenous Metabolite

Pathway

– Metabolism

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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