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IACS-8803 (diammonium)
$480 – $6,200
Products Details
Product Description
– IACS-8803 diammonium is a highly potent cyclic dinucleotide STING agonist. IACS-8803 diammonium has a robust systemic antitumor efficacy[1].
Web ID
– HY-130115B
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H29FN12O9P2S2
References
– [1]Ager CR, et al. Discovery of IACS-8803 and IACS-8779, potent agonists of stimulator of interferon genes (STING) with robust systemic antitumor efficacy. Bioorg Med Chem Lett. 2019 Oct 15;29(20):126640.
Molecular Weight
– 726.60
Compound Purity
– 99.24
SMILES
– NC1=C(C2=NC=N1)N=CN2[C@@H]3O[C@H]4[C@H]([C@H]3O[P@]([S-])(OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C7=C(N=C6)C(N)=NC=N7)F)O[P@]([S-])(OC4)=O)=O)O.[NH4+].[NH4+]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO ä¸æœ€å¤§æº¶è§£åº¦æµ‹è¯• (Clear) 15 mg/mL (ultrasonic;warming)|H2O : 15 mg/mL (ultrasonic;warming)
Target
– STING
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
