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Products Details
Product Description
– Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor that inhibit cell migration and reverse agent resistance, with an IC50 of 140 nM.
Web ID
– HY-111414
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C43H57FN2O6S
References
– [1]Jin L, et al. Discovery of 18β-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance. Bioorg Med Chem. 2018 May 1;26(8):1759-1775.
CAS Number
– 2227303-22-0
Molecular Weight
– 748.99
SMILES
– C[C@@]1(C(OCC)=O)C[C@]2([H])[C@](CC[C@]([C@@]3(C)[C@@]4([H])[C@]5(C)[C@@](C(C)(C)[C@@H](OC(CCC(NC6=NC7=C(C=C(F)C=C7)S6)=O)=O)CC5)([H])CC3)(C)C2=CC4=O)(C)CC1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HSP
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
