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Products Details
Product Description
– HSP70/SIRT2-IN-2 (Compounds 1a) is a dual inhibitor for SIRT2 and HSP70, with IC50 of 45.1±5.0 μM for SIRT2. HSP70/SIRT2-IN-2 has antitumor activity[1].
Web ID
– HY-149638
Shipping
– Room temperature
Molecular Formula
– C17H13N3S3
References
– [1]Elena Abbotto, et al. Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays. Pharmaceuticals (Basel). 2023 Sep 18;16(9):1316.
CAS Number
– 1796557-72-6
Molecular Weight
– 355.50
SMILES
– CSC1=CC(NC2=NC(C3=NC4=C(S3)C=CC=C4)=CS2)=CC=C1
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– HSP;Sirtuin
Pathway
– Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
