HS-276
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HS-276

SKU T62209-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 102 CAD through 2,544 CAD

Products Details

Product Description

– HS-276 is a highly selective, orally active inhibitor of TAK1 (Ki: 2.5 nM). HS-276 significantly inhibits TAK1 (IC50: 8.25 nM), CLK2 (IC50: 29 nM), GCK (IC50: 22 nM), ULK2 (IC50: 63 nM), MAP4K5 (IC50. HS-276 can be used to study rheumatoid arthritis (RA).

Web ID

– T62209

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H29N5O2

References

– Scarneo S, et al. Development and Efficacy of an Orally Bioavailable Selective TAK1 Inhibitor for the Treatment of Inflammatory Arthritis. ACS Chem Biol. 2022 Mar 18;17(3):536-544.

CAS Number

– 2767422-72-8

Molecular Weight

– C24H29N5O2

Compound Purity

– 0.9807

SMILES

– C(CC)N1C=2C(N=C1NC(=O)C3=CC(C(N)=O)=CC=C3)=CC=C(CN4CCCCC4)C2

Pathway

– MAPK

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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