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HS-131

Products Details

Product Description

– HS-131, a near infrared dye tethered Hsp90 inhibitor, is able to detect oncogene-driven breast cancers, including multiple different molecular subtypes of human breast cancers[1].

Web ID

– HY-122878

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C71H95N7O13S2

References

– [1]Takuya Osada, et al. In Vivo Detection of HSP90 Identifies Breast Cancers with Aggressive Behavior. Clin Cancer Res. 2017 Dec 15;23(24):7531-7542.

CAS Number

– 2084850-40-6

Molecular Weight

– 1318.68

SMILES

– CC1=NN(C2=CC(NCCCOCCOCCOCCOCCOCCCNCC3=CC=C(C=C3)C(/C=C/C4=[N+](C5=CC=CC=C5C4(C)C)CCCCS(=O)([O-])=O)=CC=C6N(C7=CC=CC=C7C6(C)C)CCCCS(=O)(O)=O)=C(C=C2)C(N)=O)C8=C1C(CC(C)(C8)C)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– HSP

Pathway

– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Dye Reagents

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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