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Products Details
Product Description
– HPK1-IN-39 (Compound 10n) is a selective HPK1 Inhibitor (IC50: 29 nM). HPK1-IN-39 inhibits the phosphorylation of SLP76. HPK1-IN-39 can be used for research of cancer immunotherapy[1].
Web ID
– HY-149520
Shipping
– Room temperature
Molecular Formula
– C26H27N7O2
References
– [1]Zhang J, et al. Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors. Bioorg Chem. 2023 Nov;140:106811.
Molecular Weight
– 469.54
SMILES
– NC(CC1)CCC1N2N=C(C3=CC=NC=C3)C(C2=N4)=CN=C4NC5=CC(C(C)(C)OC6=O)=C6C=C5
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MAP4K
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
