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HPGDS inhibitor 2
SKU
HY-126134-10 mg
Category Reference compound
Tags Immunology/Inflammation, Inflammation/Immunology, PGE synthase
$350 – $2,650
Products Details
Product Description
– HPGDS inhibitor 2 is a highly potent and selective hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with an IC50 of 9.9 nM[1].
Web ID
– HY-126134
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H24F2N2O3
References
– [1]Deaton DN, et al. The discovery of quinoline-3-carboxamides as hematopoietic prostaglandin D synthase (H-PGDS) inhibitors. Bioorg Med Chem. 2019 Apr 15;27(8):1456-1478.
CAS Number
– 2101626-26-8
Molecular Weight
– 378.41
Compound Purity
– 99.72
SMILES
– FC(F)OC1=CC=C2C(N=CC(C(N[C@@H]3CC[C@@H](C(C)(C)O)CC3)=O)=C2)=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : ≥ 150 mg/mL
Target
– PGE synthase
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.