Homoharringtonine

SKU HY-14944-10 mg Category Tags , ,

$70$383

Products Details

Product Description

– Homoharringtonine (Omacetaxine mepesuccinate;HHT) is a cytotoxic alkaloid with antitumor properties which acts by inhibiting translation elongation.

Web ID

– HY-14944

Storage Temperature

– 4°C (Powder, protect from light)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C29H39NO9

References

– [1]Cao W, et al. Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Sci Rep. 2015 Jul 13;5:8477

CAS Number

– 26833-87-4

Molecular Weight

– 545.62

Compound Purity

– 99.96

SMILES

– [H][C@@]12[C@](CCC3)(C=C(OC)[C@]2(OC([C@](CCCC(O)(C)C)(O)CC(OC)=O)=O)[H])N3CCC4=CC5=C(OCO5)C=C14

Clinical Information

– Launched

Research Area

– Cancer

Solubility

– DMSO : ≥ 50 mg/mL|H2O : 1.4 mg/mL (ultrasonic)

Target

– STAT

Isoform

– STAT3

Pathway

– JAK/STAT Signaling;Stem Cell/Wnt

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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