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Hoechst 33342
$50 – $85
Products Details
Product Description
– Hoechst 33342 is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].
Web ID
– HY-15559
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C27H28N6O
Citations
– ACS Appl Mater Interfaces. 2018 Sep 12;10(36):30081-30091.|Acs Biomater Sci Eng. 2023 Apr 11.|ACS Nano. 2023 Jul 23.|Acta Biomater. 2020 Sep 1;113:289-304.|Aging Cell. 2021 Jul;20(7):e13382.|Bioact Mater. 2022 Mar 17;18:91-103.|Biochem Biophys Res Commun. 2021 Apr 1;554:206-213.|bioRxiv. 2023 May 8.|Braz J Med Biol Res. 2021 Jan 15;54(3):e10222.|Cell Cycle. 2022 Jan 2;1-16.|Cell Death Dis. 2022 Dec 12;13(12):1034.|Cell Host Microbe. 2023 Nov 8;31(11):1820-1836.e10.|Cells. 2022 Dec 4;11(23):3923.|Chem Eng J. 15 December 2022, 138004.|Chem Eng J. 2023 Dec 2, 147850.|Chinese Pharmacological Bulletin. 2018 May; 34(5): 620-626.|Drug Deliv. 2017 Nov;24(1):1453-1459. |Environ Sci Technol. 2017 Sep 19;51(18):10834-10842.|Eur J Med Chem. 2023 Jan 5;245(Pt 2):114919.|Front Biosci (Landmark Ed). 2022, 27(9), 260.|Hum Mol Genet. 2023 May 3;ddad070.|J Cell Biol. 2021 Oct 4;220(10):e202011153.|J Innate Immun. 2022 Oct 21;1-21.|J Lipid Res. 2022 May;63(5):100207.|J Obstet Gynaecol Res. 2020 Sep 17;46(12):2561-2572.|J Pain Res. 2021 Feb 4;14:297-310.|Mar Drugs. 2023 Nov 21, 21(12), 600.|Neural Regen Res. 2022 Sep;17(9):2029-2035.|Neural Regen Res. 2023 Jun;18(6):1339-1346.|Oncol Lett. 2023 Nov 16.|PeerJ. 2022 Sep 28;10:e14086.|Science. 2022 Nov 18;378(6621):eabq7361.|Small. 2021 Aug;17(32):e2101368.|Stem Cell Res Ther. 2021 Jan 22;12(1):77.|Theranostics. 2021 Mar 4;11(10):4655-4671.|Cancer Biol Ther. 2018;19(12):1193-1203. |Cancer Pathog Ther. 2023 Mar 7.|J Cell Physiol. 2021 Jul;236(7):5278-5292.|J Ethnopharmacol. 2022 Jan 29;289:115039.|J Ethnopharmacol. 8 October 2021, 114730.|J Orthop Translat. 17 October 2022.|Radiother Oncol. 2023 Nov 29:110039.|Stem Cells Int. 15 Aug 2021.
References
– [1]Chazotte B. Labeling nuclear DNA with hoechst 33342. Cold Spring Harb Protoc. 2011 Jan 1;2011(1):pdb.prot5557.
CAS Number
– 23491-52-3
Molecular Weight
– 452.55
Compound Purity
– 99.94
SMILES
– CN1CCN(C2=CC=C3C(N=C(C4=CC=C5C(N=C(C6=CC=C(OCC)C=C6)N5)=C4)N3)=C2)CC1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 6.25 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : < 0.1 mg/mL
Target
– Autophagy
Pathway
– Autophagy
Product type
– Dye Reagents
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
