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Products Details
Product Description
– HNHA is a potent histone deacetylase (HDAC) inhibitor. HNHA arrests the cell cycle at the G1/S phase via p21 induction. HNHA inhibits tumor growth and tumor neovascularization. HNHA may be a potent anti-cancer agent against breast cancer[1].
Web ID
– HY-118672
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C17H21NO2S
References
– [1]Park KC, et al. Potential anti-cancer activity of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a histone deacetylase inhibitor, against breast cancer both in vitro and in vivo. Cancer Sci. 2011 Feb;102(2):343-50.
CAS Number
– 926908-04-5
Molecular Weight
– 303.42
SMILES
– O=C(NO)CCCCCCSC1=CC=C2C=CC=CC2=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC;HIF/HIF Prolyl-Hydroxylase;MMP
Isoform
– MMP-2;MMP-9
Pathway
– Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease
Product type
– Reference compound
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