HM03

$60$600

Products Details

Product Description

– HM03 is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 has anticancer activity[1].

Web ID

– HY-125974

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C26H27ClN4O2

References

– [1]Huang M, et al. Structure-based design of HSPA5 inhibitors: from peptide to small molecule inhibitors. Bioorg Med Chem Lett. 2013;23(10):3044‐3050.

CAS Number

– 500565-15-1

Molecular Weight

– 462.97

Compound Purity

– 99.34

SMILES

– OC1=CC=C(NC2=C(C=C(OC)C=C3)C3=NC4=CC(Cl)=CC=C42)C=C1CN5CCN(C)CC5

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– HSP

Isoform

– HSPA5

Pathway

– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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