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Products Details
Product Description
– HJC0152 (free base) is an orally active and potent inhibitor of STAT3. HJC0152 (free base) inhibits cell cycle progression and induces apoptosis. HJC0152 (free base) significantly suppresses MDA-MB-231 xenograft tumor growth in mice[1].
Web ID
– HY-W369099
Shipping
– Room temperature
Molecular Formula
– C15H13Cl2N3O4
References
– [1]Chen H, et al. Discovery of O-Alkylamino Tethered Niclosamide Derivatives as Potent and Orally Bioavailable Anticancer Agents. ACS Med Chem Lett. 2013 Feb 14;4(2):180-185.
CAS Number
– 1420290-88-5
Molecular Weight
– 370.19
SMILES
– NCCOC1=C(C=C(Cl)C=C1)C(=O)NC2=C(Cl)C=C([N+](=O)[O-])C=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis, STAT
Pathway
– Apoptosis, JAK/STAT Signaling, Stem Cell/Wnt
Product type
– Reference compound
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