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HIF-1 inhibitor-4
$120 – $990
Products Details
Product Description
– HIF-1 inhibitor-4 is a HIF-1 inhibitor (IC50: 560 nM). HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level[1].
Web ID
– HY-153017
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C18H19IN2O2
References
– [1]Nagao S, et al. Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors. Bioorg Med Chem. 2014 Oct 1;22(19):5513-29.
CAS Number
– 333357-56-5
Molecular Weight
– 422.26
Compound Purity
– 99.50
SMILES
– O=C(C1=CC=C(CN2CCOCC2)C=C1)NC3=CC=C(C=C3)I
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
