Download Files:
HexylHIBO
$131
Products Details
Product Description
– HexylHIBO is a potent group I mGluR antagonist with Kbs of 140 and 110 μM at mGlu1a and mGlu5a receptors, respectively. HexylHIBO decreased sEPSC in rat[1].
Web ID
– HY-103559
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C12H20N2O4
References
– [1]Madsen U, et al. Synthesis and pharmacology of 3-isoxazolol amino acids as selective antagonists at group I metabotropic glutamic acid receptors. J Med Chem. 2001;44(7):1051-1059.|[2]Bandrowski AE, et al, Prince DA. Baseline glutamate levels affect group I and II mGluRs in layer V pyramidal neurons of rat sensorimotor cortex. J Neurophysiol. 2003;89(3):1308-1316.
CAS Number
– 334887-43-3
Molecular Weight
– 256.30
SMILES
– O=C(O)C(N)CC(ON1)=C(CCCCCC)C1=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mGluR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
