Download Files:
Products Details
Product Description
– Henagliflozin (SHR3824) is a potent selective sodium-glucose co-transporter 2 (SGLT2) inhibitor with the IC50 values of 2.38 and 4324 nM for human SGLT2 and SGLT1, respectively. Henagliflozin can be used in diabetes research[1].
Web ID
– HY-123011
Shipping
– Room temperature
Molecular Formula
– C22H24ClFO7
References
– [1]Pang-ke Yan, et al. SHR3824, a novel selective inhibitor of renal sodium glucose cotransporter 2, exhibits antidiabetic efficacy in rodent models. Acta Pharmacol Sin. 2014 May;35(5):613-24.Â
CAS Number
– 1623804-44-3
Molecular Weight
– 454.87
SMILES
– O[C@H]1[C@@]2(C3=CC(CC4=CC(F)=C(C=C4)OCC)=C(C=C3)Cl)O[C@](CO2)([C@H]([C@@H]1O)O)CO
Clinical Information
– Phase 4
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– SGLT
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
