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Products Details
Product Description
– Heliosupine N-oxide, Heliosupin metabolite, inhibits muscarinic acetylcholine receptor (mAChR) with the IC50 of 350 μM. Heliosupine N-oxide is a pyrrolizidine alkaloid (PA)[1].
Web ID
– HY-131574
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C20H31NO8
References
– [1]T. Schmeller, et al. Allelochemical Activities of Pyrrolizidine Alkaloids: Interactions with Neuroreceptors and Acetylcholine Related Enzymes.Journal of Chemical Ecology volume 23, pages399–416 (1997).
CAS Number
– 31701-88-9
Molecular Weight
– 413.46
SMILES
– [O-][N+]12[C@]([C@H](CC2)OC(/C(C)=CC)=O)([H])C(COC([C@@]([C@@H](O)C)(O)C(C)(O)C)=O)=CC1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– mAChR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
