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HEC72702
Products Details
Product Description
– HEC72702 is a potent and orally active hepatitis B virus capsid inhibitor with an EC50 values of 0.039 µM. HEC72702 dose-dependently reduced HBV DNA in both the plasma and livers[1].
Web ID
– HY-123767
Shipping
– Room temperature
Molecular Formula
– C24H26BrFN4O5S
References
– [1]Ren Q, et al. 3-((R)-4-(((R)-6-(2-Bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholin-2-yl)propanoic Acid (HEC72702), a Novel Hepatitis B Virus Capsid Inhibitor Based on Clinical Candidate GLS4. J Med Chem. 2018 Feb 8;61(3):1355-1374.
CAS Number
– 1793063-59-8
Molecular Weight
– 581.45
SMILES
– O=C(O)CC[C@@H]1CN(CC2=C(C(OCC)=O)[C@H](C3=CC=C(F)C=C3Br)N=C(C4=NC=CS4)N2)CCO1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HBV
Pathway
– Anti-infection
Product type
– Reference compound
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