HDAC8-IN-1
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HDAC8-IN-1

SKU T7082-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 830 CAD

Products Details

Product Description

– MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1].

Web ID

– T7082

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H19NO3

References

– Huang WJ, et al. Synthesis and biological evaluation of ortho-aryl N-hydroxycinnamides as potent histone deacetylase (HDAC) 8 isoform-selective inhibitors. ChemMedChem. 2012 Oct;7(10):1815-24.

CAS Number

– 1417997-93-3

Molecular Weight

– C22H19NO3

Compound Purity

– 0.9983

SMILES

– COc1ccc(C=CC(=O)NO)c(c1)-c1ccc(cc1)-c1ccccc1

Pathway

– DNA Damage/DNA Repair|||Chromatin/Epigenetic

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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