Products Details

Product Description

– HDAC-IN-44 is a HDAC inhibitor with the IC50 value of 61.2 nM. HDAC-IN-44 shows high anticancer activity towards multiple cancer cell lines[1].

Web ID

– HY-150500

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C26H27BrN4O4

References

– [1]Ahmed K ElHady et al. Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103742.

CAS Number

– 2414921-46-1

Molecular Weight

– 539.42

SMILES

– O=C(NO)CCCCCN(C1)C([C@]2([H])CC3=C([C@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– HDAC

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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