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Products Details
Product Description
– HDAC-IN-44 is a HDAC inhibitor with the IC50 value of 61.2 nM. HDAC-IN-44 shows high anticancer activity towards multiple cancer cell lines[1].
Web ID
– HY-150500
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C26H27BrN4O4
References
– [1]Ahmed K ElHady et al. Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103742.
CAS Number
– 2414921-46-1
Molecular Weight
– 539.42
SMILES
– O=C(NO)CCCCCN(C1)C([C@]2([H])CC3=C([C@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
