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HDAC-IN-41

SKU HY-147840-Get quote Category Tags , ,

Products Details

Product Description

– HDAC-IN-41 (Compound 7c) is a selective, orally active class I HDAC inhibitor with IC50 values of 0.62, 1.46 and 0.62 μM against HDAC1, HDAC2 and HDAC3, respectively. HDAC-IN-41 shows NO releasing activity[1].

Web ID

– HY-147840

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C20H22N4O6S

References

– [1]Ding Q, et al. Synthesis and biological study of class I selective HDAC inhibitors with NO releasing activity. Bioorg Chem. 2020 Nov;104:104235.

CAS Number

– 2490309-83-4

Molecular Weight

– 446.48

SMILES

– O=S(C1=[N+]([O-])ON=C1OCCCCCC(NC2=C(N)C=CC=C2)=O)(C3=CC=CC=C3)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– HDAC

Isoform

– HDAC1;HDAC2;HDAC3

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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