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Products Details
Product Description
– HDAC-IN-32 is a potent HDAC inhibitor with IC50s of 5.2, 11, and 28 nM for HDAC1, HDAC2 and HDAC6, respectively. HDAC-IN-32 possesses potent antiproliferation activities against tumor cells. HDAC-IN-32 shows potent antitumor efficacy in vivo That trigger antitumor immunity[1].
Web ID
– HY-145687
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H23N3O3
References
– [1]”Chen C, et al. Discovery of DNA-Targeting HDAC Inhibitors with Potent Antitumor Efficacy In Vivo That Trigger Antitumor Immunity. J Med Chem. 2022 Feb 24;65(4):3667-3683.
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CAS Number
– 2766688-17-7
Molecular Weight
– 353.41
SMILES
– O=C(NO)CCCCCCOC1=CC=CC(C2=NC3=CC=CC=C3N2)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
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