Products Details

Product Description

– HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC50 value of 4.7 nM.

Web ID

– HY-145350

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C24H28FN5O3

References

– [1]Liu J, Kelly J, Yu W, Clausen D, Yu Y, Kim H, Duffy JL, Chung CC, Myers RW, Carroll S, Klein DJ, Fells J, Holloway MK, Wu J, Wu G, Howell BJ, Barnard RJO, Kozlowski JA. Selective Class I HDAC Inhibitors Based on Aryl Ketone Zinc Binding Induce HIV-1 Protein for Clearance. ACS Med Chem Lett. 2020 Jun 22;11(7):1476-1483.

CAS Number

– 2410542-97-9

Molecular Weight

– 453.51

SMILES

– FC1=C(C=CC=C1)C2=CN=C([C@H](CCCCCC(C3=NOC=C3)=O)NC(C4CN(C4)C)=O)N2

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– HDAC

Pathway

– Cell Cycle/DNA Damage;Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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