HCV-IN-7 (hydrochloride)

SKU HY-133018A-Get quote Category Tags , ,

Products Details

Product Description

– HCV-IN-7 hydrochloride is an orally active and potent pan-genotypic HCV NS5A inhibitor with IC50s of 3-47 pM. HCV-IN-7 hydrochloride shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake. HCV-IN-7 hydrochloride has anti-viral activity[1].

Web ID

– HY-133018A

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C40H50Cl2N8O6S

References

– [1]Ramdas V, et al. Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate. J Med Chem. 2019 Dec 12;62(23):10563-10582.

CAS Number

– 1449756-87-9

Molecular Weight

– 841.85

SMILES

– [H]Cl.[H]Cl.O=C([C@H](C(C)C)NC(OC)=O)N(CCC1)[C@@H]1C(N2)=NC=C2C3=CC(C=C4)=C(S3)C5=C4C=C(C6=CN=C([C@H]7N(C([C@H](C(C)C)NC(OC)=O)=O)CCC7)N6)C=C5

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– HCV

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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