Hck-IN-1
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Hck-IN-1

SKU T11538-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 157 CAD through 2,544 CAD

Products Details

Product Description

– Hck-IN-1 is a selective Nef-dependent Hck inhibitor (IC50s: 2.8 μM and >20 μM for Nef:Hck complex and Hck) with antiretroviral activity. Hck-IN-1 is a direct and wide HIV-1 Nef antagonist with an IC50 of 100-300 nM for wild-type HIV-1 replication.

Web ID

– T11538

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C16H11ClN6O3S

References

– Emert-Sedlak LA, et al. Effector kinase coupling enables high-throughput screens for direct HIV-1 Nef antagonists with antiretroviral activity. Chem Biol. 2013 Jan 24;20(1):82-91.

CAS Number

– 1473404-51-1

Molecular Weight

– C16H11ClN6O3S

Compound Purity

– 0.9907

SMILES

– NC(=S)n1nc(c(N=Nc2cccc(Cl)c2)c1O)-c1ccc(cc1)[N+]([O-])=O

Target

– Others

Pathway

– Tyrosine Kinase/Adaptors|||Proteases/Proteasome|||Angiogenesis|||Microbiology/Virology

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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