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Products Details
Product Description
– hCAII-IN-9 is a potent carbonic anhydrase inhibitor with IC50s of 1.18 μM (hCA II), 0.17 μM (hCA IX), and 2.99 μM (hCA XII), respectively. hCAII-IN-9 has no blood-brain barrier permeability[1].
Web ID
– HY-152141
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C15H16ClN3O5S2
References
– [1]Hussain Z, et al. Synthesis and Evaluation of Amide and Thiourea Derivatives as Carbonic Anhydrase (CA) Inhibitors. ACS Omega. 2022 Dec 6;7(50):47251-47264.
CAS Number
– 2878477-18-8
Molecular Weight
– 417.89
SMILES
– CC1=CC(C)=CC(C(NC2=CC(Cl)=C(C=C2S(N)(=O)=O)S(N)(=O)=O)=O)=C1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– Carbonic Anhydrase
Isoform
– CA â…¡;CA â…¨;CA XII
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
