HB007

SKU T37646-25 mg Category Brand:

Price range: 1,366 CAD through 2,576 CAD

Products Details

Product Description

– HB007 is a potent degrader of small ubiquitin-related modifier 1 (SUMO1). It mediates the ubiquitination and subsequent degradation of SUMO1, leading to a decrease in tumor growth in vivo. HB007 is a valuable tool for investigating brain, breast, colon, and lung cancers[1][2].

Web ID

– T37646

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C15H9ClN4OS

References

– Bellail AC, et, al. Ubiquitination and degradation of SUMO1 by small-molecule degraders extends survival of mice with patient-derived tumors. Sci Transl Med. 2021 Oct 13;13(615):eabh1486.

CAS Number

– 2387821-46-5

Molecular Weight

– C15H9ClN4OS

SMILES

– Clc1cccc(NC(=O)Nc2nc3ccc(cc3s2)C#N)c1

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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