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GW 501516
Price range: 69 CAD through 245 CAD
Products Details
Product Description
– GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.
Web ID
– T6151
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H18F3NO3S2
Citations
– 1. Han W, Wang N, Kong R, et al. Ligand-activated PPARδ expression promotes hepatocellular carcinoma progression by regulating the PI3K-AKT signaling pathway. Journal of Translational Medicine. 2022, 20(1): 1-14.
2. Ren Q, Xie X, Zhao C, et al. 2, 2′, 4, 4′-Tetrabromodiphenyl Ether (PBDE 47) Selectively Stimulates Proatherogenic PPARγ Signatures in Human THP-1 Macrophages to Contribute to Foam Cell Formation. Chemical Research in Toxicology. 2022
References
– Wei ZL, et al. A short and efficient synthesis of the pharmacological research tool GW501516 for the peroxisome proliferator-activated receptor delta. J Org Chem. 2003 Nov 14;68(23):9116-8.
CAS Number
– 317318-70-0
Molecular Weight
– C21H18F3NO3S2
Compound Purity
– 0.9964
SMILES
– C(SC1=CC(C)=C(OCC(O)=O)C=C1)C=2SC(=NC2C)C3=CC=C(C(F)(F)F)C=C3
Pathway
– Metabolism|||Autophagy|||DNA Damage/DNA Repair
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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