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Gü2602
$300 – $2,400
Products Details
Product Description
– Gü2602 is a potent, reversible cathepsin K (CatK) inhibitor with a Ki of 0.013 nM for mature CatK (mCatK). Gü2602 suppresses the autocatalytic activation of the cathepsin K zymogen[1].
Web ID
– HY-144813
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H22N4O3
References
– [1]Benýšek J, et al. Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes. J Enzyme Inhib Med Chem. 2022 Dec;37(1):515-526.
CAS Number
– 1627094-88-5
Molecular Weight
– 318.37
Compound Purity
– 98.13
SMILES
– CN(C(CN(NC(OC(C)(C)C)=O)C#N)=O)CC1=CC=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 66.67 mg/mL (ultrasonic)
Target
– Cathepsin
Isoform
– Cathepsin K
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
