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GSK840
Price range: 51 CAD through 477 CAD
Products Details
Product Description
– GSK840 (GSK’840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor that binds to the RIP3 kinase domain (IC50: 0.9 nM) and inhibits kinase activity (IC50: 0.3 nM).
Web ID
– T11501
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C21H23N3O3
Citations
– 1. Tu X, Zou Z, Li J, et al.Artificial intelligence-enabled discovery of a RIPK3 inhibitor with neuroprotective effects in an acute glaucoma mouse model.Chinese Medical Journal.2024: 10.1097.
References
– Mandal P, et al. RIP3 induces apoptosis independent of pronecrotic kinase activity. Mol Cell. 2014 Nov 20;56(4):481-95.
CAS Number
– 2361146-30-5
Molecular Weight
– C21H23N3O3
Compound Purity
– 0.997
SMILES
– CNC(=O)c1ccc2n(cnc2c1)-c1ccc(CC(=O)OC(C)(C)C)cc1
Target
– Others
Pathway
– Apoptosis|||NF-κB
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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