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Products Details
Product Description
– GSK3735967 is a selective, reversible, non-nucleoside inhibitor targeting DNMT1, demonstrating an IC50 value of 40 nM. It features a planar dicyanopyridine core designed to specifically interact with DNMT1-bound hemimethylated CpG dinucleotides. Additionally, GSK3735967 possesses three binding sites, with one uniquely capable of binding to histone H4K20me3 [1] [2].
Web ID
– T74887
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C25H31N7OS
CAS Number
– 2170136-86-2
Molecular Weight
– C25H31N7OS
SMILES
– C(#N)C1=C(N=C(SCC2=CC=C(CNC(CN)=O)C=C2)C(C#N)=C1CC)N3CCN(C)CCC3
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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