GSK3145095

SKU HY-111946-1 mg Category Tags , ,

$120$3,200

Products Details

Product Description

– GSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM [1].

Web ID

– HY-111946

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-Kinase/protease

Molecular Formula

– C20H17F2N5O2

References

– [1]Harris PA, ET AL. Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer. ACS Med Chem Lett. 2019 May 9;10(6):857-862.

CAS Number

– 1622849-43-7

Molecular Weight

– 397.38

Compound Purity

– 99.39

SMILES

– FC1=CC(F)=CC2=C1NC([C@@H](NC(C3=NNC(CC4=CC=CC=C4)=N3)=O)CC2)=O

Clinical Information

– Phase 2

Research Area

– Cancer

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– RIP kinase

Pathway

– Apoptosis

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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