GSK3145095

SKU T15437-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 155 CAD through 1,579 CAD

Products Details

Product Description

– GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.

Web ID

– T15437

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H17F2N5O2

References

– Harris PA, ET AL. Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer. ACS Med Chem Lett. 2019 May 9;10(6):857-862.

CAS Number

– 1622849-43-7

Molecular Weight

– C20H17F2N5O2

Compound Purity

– 1

SMILES

– Fc1cc(F)c2NC(=O)[C@H](CCc2c1)NC(=O)c1n[nH]c(Cc2ccccc2)n1

Target

– Others

Pathway

– NF-κB|||Apoptosis

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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