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GSK3145095
$120 – $3,200
Products Details
Product Description
– GSK3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM [1].
Web ID
– HY-111946
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C20H17F2N5O2
References
– [1]Harris PA, ET AL. Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer. ACS Med Chem Lett. 2019 May 9;10(6):857-862.
CAS Number
– 1622849-43-7
Molecular Weight
– 397.38
Compound Purity
– 99.39
SMILES
– FC1=CC(F)=CC2=C1NC([C@@H](NC(C3=NNC(CC4=CC=CC=C4)=N3)=O)CC2)=O
Clinical Information
– Phase 2
Research Area
– Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– RIP kinase
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
