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GSK269962A
Price range: 58 CAD through 926 CAD
Products Details
Product Description
– GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.
Web ID
– T3518
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C29H30N8O5
Citations
– 1. Xu Q, Fu Q, Li Z, et al. Procyanidin C1 is a natural agent with senolytic activity against aging and age-related diseases. EMBO Molecular Medicine. (2021)13:e12716
2. Mondal T, Shivange G N, Tihagam R G T, et al. Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies. EMBO Molecular Medicine. 2021 Mar 5;13(3):e12716. doi: 10.15252/emmm.202012716. Epub 2021 Feb 15.
References
– Doe C, et al. J Pharmacol Exp Ther. 2007, 320(1):89-98.
CAS Number
– 850664-21-0
Molecular Weight
– C29H30N8O5
Compound Purity
– 0.9971
SMILES
– CCn1c(nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc12)-c1nonc1N
Target
– Others
Pathway
– PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||MAPK|||Stem Cells
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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