GSK269962A

SKU T3518-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 926 CAD

Products Details

Product Description

– GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.

Web ID

– T3518

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C29H30N8O5

Citations

– 1. Xu Q, Fu Q, Li Z, et al. Procyanidin C1 is a natural agent with senolytic activity against aging and age-related diseases. EMBO Molecular Medicine. (2021)13:e12716 2. Mondal T, Shivange G N, Tihagam R G T, et al. Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies. EMBO Molecular Medicine. 2021 Mar 5;13(3):e12716. doi: 10.15252/emmm.202012716. Epub 2021 Feb 15.

References

– Doe C, et al. J Pharmacol Exp Ther. 2007, 320(1):89-98.

CAS Number

– 850664-21-0

Molecular Weight

– C29H30N8O5

Compound Purity

– 0.9971

SMILES

– CCn1c(nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc12)-c1nonc1N

Target

– Others

Pathway

– PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling|||MAPK|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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