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GSK269962A
$106 – $792
Products Details
Product Description
– GSK269962A (GSK 269962) is a potent ROCK inhibitor with IC50s of 1.6 and 4 nM for recombinant human ROCK1 and ROCK2 respectively. GSK269962A has anti-inflammatory and vasodilatory activities[1].
Web ID
– HY-15556
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C29H30N8O5
References
– [1]Doe C, et al. Novel Rho kinase inhibitors with anti-inflammatory and vasodilatory activities. J Pharmacol Exp Ther. 2007 Jan;320(1):89-98.
CAS Number
– 850664-21-0
Molecular Weight
– 570.60
Compound Purity
– 99.83
SMILES
– CCN1C2=CC(OC3=CC=CC(NC(C4=CC=C(OCCN5CCOCC5)C=C4)=O)=C3)=NC=C2N=C1C6=NON=C6N
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology; Cardiovascular Disease
Solubility
– DMSO : ≥ 30 mg/mL
Target
– ROCK
Isoform
– ROCK1;ROCK2
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
