GSK199

$125$480

Products Details

Product Description

– GSK199 is a reversible and selective PAD4 inhibitor with an IC50 of 200 nM in the absence of calcium[1].

Web ID

– HY-103058

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C24H29ClN6O2

References

– [1]Lewis HD, et al. Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. Nat Chem Biol. 2015 Mar;11(3):189-91.

CAS Number

– 1549811-53-1

Molecular Weight

– 468.98

Compound Purity

– 99.86

SMILES

– O=C(N1C[C@H](N)CCC1)C2=CC(OC)=C3C(N=C(C4=CC5=CC=CN=C5N4CC)N3C)=C2.[H]Cl

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology; Cardiovascular Disease

Solubility

– DMSO : 125 mg/mL (ultrasonic)

Target

– Protein Arginine Deiminase

Pathway

– Epigenetics

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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